Simethicone 100% is an anti-foaming agent used to relieve bloating, discomfort, or pain caused by excess gas in the stomach or intestines. Here's a detailed overview:
Simethicone is a silicone-based compound (made from dimethicone and silica gel) that works by reducing the surface tension of gas bubbles in the gastrointestinal (GI) tract. It helps gas bubbles combine into larger bubbles, which are more easily passed either by burping or flatulence.
Relief of gas, bloating, and fullness in the stomach
Helps manage infant colic (in drops form)
Used before diagnostic procedures (like endoscopy) to reduce gas bubbles for better imaging
Simethicone does not absorb into the bloodstream. It stays in the GI tract and is excreted unchanged. It physically changes how gas bubbles behave, but it does not prevent gas formationit just helps remove it more comfortably.
Simethicone 100% typically means pure simethicone without added active ingredients. It's usually found in:
Tablets (chewable or swallow)
Softgels
Liquid drops (especially for infants)
Suspensions
Dosage varies depending on age and formulation:
Adults: 40125 mg after meals and at bedtime (max 500 mg/day depending on brand)
Infants: Often 20 mg (0.3 mL liquid) 4x/day as needed
Always follow the product label or healthcare provider's instructions.
Simethicone is very well tolerated. Side effects are rare but may include:
Mild diarrhea
Nausea
Allergic reactions (very rare)
Gas-X
Phazyme
Mylicon (infants)
Infacol (UK)
Generic/store brands
Simethicone is considered safe with most medications and no significant drug interactions are known. However, it may affect the absorption of thyroid medications if taken at the same time.
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